D10N (p.Asp10Asn) variant of SRC (P12931)
D10N (p.Asp10Asn) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, experimental measurements, and structural context.
D10N (p.Asp10Asn) variant details
- p.Asp10Asn
- gnomAD rs1251001677
- Missense
- Variant Prioritization Score for Impact Estimate 0.437
- REVEL 0.22
- CADD 23.90
- PolyPhen-2 0.07
- SIFT 0.14
- Most common in the East Asian population (allele frequency 5.2e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.245