A34G (p.Ala34Gly) variant of SRC (P12931)
A34G (p.Ala34Gly) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A34G (p.Ala34Gly) variant details
- p.Ala34Gly
- gnomAD 20-37384254-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.15
- MetaLR 0.26
- MetaSVM -0.80
- CADD 14.30
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- SRC SH3 domain domainome 1.0: score 0.0404
- Literature evidence available