A31T (p.Ala31Thr) variant of SRC (P12931)
A31T (p.Ala31Thr) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A31T (p.Ala31Thr) variant details
- p.Ala31Thr
- gnomAD rs1437496392
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.14
- CADD 19.30
- PolyPhen-2 0.02
- SIFT 0.40
- Most common in the East Asian population (allele frequency 2.9e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0393