A31S (p.Ala31Ser) variant of SRC (P12931)
A31S (p.Ala31Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A31S (p.Ala31Ser) variant details
- p.Ala31Ser
- gnomAD 20-37384244-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.12
- MetaLR 0.11
- MetaSVM -0.92
- CADD 17.70
- PolyPhen-2 0.00
- SIFT 0.83
- Most common in the East Asian population (allele frequency 2.9e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0393
- Literature evidence available