A31G (p.Ala31Gly) variant of SRC (P12931)
A31G (p.Ala31Gly) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A31G (p.Ala31Gly) variant details
- p.Ala31Gly
- gnomAD 20-37384245-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.18
- MetaLR 0.14
- MetaSVM -0.89
- CADD 20.20
- PolyPhen-2 0.01
- SIFT 0.45
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.0393
- Literature evidence available