A27V (p.Ala27Val) variant of SRC (P12931)
A27V (p.Ala27Val) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A27V (p.Ala27Val) variant details
- p.Ala27Val
- gnomAD 20-37384233-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.11
- MetaLR 0.18
- MetaSVM -0.98
- CADD 6.68
- PolyPhen-2 0.01
- SIFT 0.12
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -1
- Literature evidence available