A27S (p.Ala27Ser) variant of SRC (P12931)
A27S (p.Ala27Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A27S (p.Ala27Ser) variant details
- p.Ala27Ser
- gnomAD 20-37384232-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.145
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -0.95
- CADD 7.04
- PolyPhen-2 0.01
- SIFT 0.58
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -1
- Literature evidence available