A21T (p.Ala21Thr) variant of SRC (P12931)
A21T (p.Ala21Thr) in SRC (P12931) is a missense change. The available record places it in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A21T (p.Ala21Thr) variant details
- p.Ala21Thr
- rs367543238
- ClinGen CA226013
- cosmic curated COSV62441
- ClinVar RCV000084815
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.113
- REVEL 0.14
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.81
- ClinVar: not provided (not provided)
- UniProt: Not provided
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.879