A21S (p.Ala21Ser) variant of SRC (P12931)
A21S (p.Ala21Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD 20-37384214-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.14
- MetaLR 0.10
- MetaSVM -0.98
- CADD 0.00
- PolyPhen-2 0.01
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- SRC SH3 domain domainome 1.0: score -0.879
- Literature evidence available