A11V (p.Ala11Val) variant of SRC (P12931)
A11V (p.Ala11Val) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, and structural context.
A11V (p.Ala11Val) variant details
- p.Ala11Val
- gnomAD rs1212841399
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.11
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.2e-05)
- Structural context available
- SRC SH3 domain domainome 1.0: score -1.08