A11S (p.Ala11Ser) variant of SRC (P12931)
A11S (p.Ala11Ser) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A11S (p.Ala11Ser) variant details
- p.Ala11Ser
- gnomAD 20-37384184-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.12
- MetaLR 0.19
- MetaSVM -1.00
- CADD 20.40
- PolyPhen-2 0.01
- SIFT 0.24
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -1.08
- Literature evidence available