A11D (p.Ala11Asp) variant of SRC (P12931)
A11D (p.Ala11Asp) in SRC (P12931) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
A11D (p.Ala11Asp) variant details
- p.Ala11Asp
- gnomAD 20-37384185-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.29
- MetaLR 0.20
- MetaSVM -0.97
- CADD 22.50
- PolyPhen-2 0.03
- SIFT 0.12
- Population evidence available
- Structural context available
- SRC SH3 domain domainome 1.0: score -1.08
- Literature evidence available