Y9Y (p.Tyr9Tyr) variant of SQSTM1 (Sequestosome-1)
Y9Y (p.Tyr9Tyr) in SQSTM1 (Sequestosome-1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Y9Y (p.Tyr9Tyr) variant details
- p.Tyr9Tyr
- gnomAD 5-179820963-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.197
- CADD 11.70
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- SQSTM1 Zinc finger, ZZ-type domain domainome 1.0: score -1.08
- Literature evidence available