S24S (p.Ser24Ser) variant of SQSTM1 (Sequestosome-1)
S24S (p.Ser24Ser) in SQSTM1 (Sequestosome-1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S24S (p.Ser24Ser) variant details
- p.Ser24Ser
- rs774460525
- gnomAD 5-179821008-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.327
- CADD 16.30
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- SQSTM1 Sequestosome-1, UBA domain domainome 1.0: score -0.346
- Literature evidence available