L4L (p.Leu4Leu) variant of SQSTM1 (Sequestosome-1)
L4L (p.Leu4Leu) in SQSTM1 (Sequestosome-1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
L4L (p.Leu4Leu) variant details
- p.Leu4Leu
- gnomAD 5-179820948-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.669
- CADD 11.30
- Population evidence available
- Structural context available
- SQSTM1 Sequestosome-1, UBA domain domainome 1.0: score -0.404
- Literature evidence available