F25F (p.Phe25Phe) variant of SQSTM1 (Sequestosome-1)
F25F (p.Phe25Phe) in SQSTM1 (Sequestosome-1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
F25F (p.Phe25Phe) variant details
- p.Phe25Phe
- gnomAD 5-179821011-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.51
- CADD 15.90
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available
- SQSTM1 Sequestosome-1, UBA domain domainome 1.0: score -0.427
- Literature evidence available