D15Y (p.Asp15Tyr) variant of SQSTM1 (Sequestosome-1)
D15Y (p.Asp15Tyr) in SQSTM1 (Sequestosome-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D15Y (p.Asp15Tyr) variant details
- p.Asp15Tyr
- gnomAD 5-179820979-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.41
- REVEL 0.24
- CADD 26.10
- PolyPhen-2 0.17
- SIFT 0.00
- Population evidence available
- Structural context available
- SQSTM1 Zinc finger, ZZ-type domain domainome 1.0: score -0.347
- Literature evidence available