D15V (p.Asp15Val) variant of SQSTM1 (Sequestosome-1)
D15V (p.Asp15Val) in SQSTM1 (Sequestosome-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D15V (p.Asp15Val) variant details
- p.Asp15Val
- gnomAD 5-179820980-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.14
- CADD 24.80
- PolyPhen-2 0.06
- SIFT 0.02
- Population evidence available
- Structural context available
- SQSTM1 Zinc finger, ZZ-type domain domainome 1.0: score -0.347
- Literature evidence available