D15G (p.Asp15Gly) variant of SQSTM1 (Sequestosome-1)
D15G (p.Asp15Gly) in SQSTM1 (Sequestosome-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, experimental measurements, and structural context.
D15G (p.Asp15Gly) variant details
- p.Asp15Gly
- Ensembl rs1757751748
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.15
- CADD 23.70
- PolyPhen-2 0.00
- SIFT 0.21
- Population evidence available
- Structural context available
- SQSTM1 Zinc finger, ZZ-type domain domainome 1.0: score -0.347