D15D (p.Asp15Asp) variant of SQSTM1 (Sequestosome-1)
D15D (p.Asp15Asp) in SQSTM1 (Sequestosome-1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D15D (p.Asp15Asp) variant details
- p.Asp15Asp
- rs1757751804
- gnomAD 5-179820981-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.131
- CADD 7.14
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available
- SQSTM1 Zinc finger, ZZ-type domain domainome 1.0: score -0.347
- Literature evidence available