M37T (p.Met37Thr) variant of SPINK5 (Q9NQ38)
M37T (p.Met37Thr) in SPINK5 (Q9NQ38) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
M37T (p.Met37Thr) variant details
- p.Met37Thr
- gnomAD rs1752704518
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.07
- MetaLR 0.03
- MetaSVM -1.08
- CADD 23.10
- PolyPhen-2 0.43
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available