Y121R (p.Tyr121Arg) variant of SPI1 (Transcription factor PU.1)

Y121R (p.Tyr121Arg) in SPI1 (Transcription factor PU.1) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The record also includes structural context.

Y121R (p.Tyr121Arg) variant details