F10Y (p.Phe10Tyr) variant of SPI1 (Transcription factor PU.1)
F10Y (p.Phe10Tyr) in SPI1 (Transcription factor PU.1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
F10Y (p.Phe10Tyr) variant details
- p.Phe10Tyr
- TOPMed rs1260363610
- gnomAD rs1260363610
- Missense
- Variant Prioritization Score for Impact Estimate 0.293
- REVEL 0.10
- MetaLR 0.03
- MetaSVM -1.04
- CADD 22.60
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available