P25S (p.Pro25Ser) variant of SPG7 (Q9UQ90)
P25S (p.Pro25Ser) in SPG7 (Q9UQ90) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
P25S (p.Pro25Ser) variant details
- p.Pro25Ser
- gnomAD 16-89508490-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.348
- CADD 2.90
- PolyPhen-2 0.00
- SIFT 0.75
- Population evidence available
- Structural context available
- Literature evidence available