P15Q (p.Pro15Gln) variant of SPG7 (Q9UQ90)
P15Q (p.Pro15Gln) in SPG7 (Q9UQ90) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
P15Q (p.Pro15Gln) variant details
- p.Pro15Gln
- gnomAD 16-89508461-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- CADD 9.15
- PolyPhen-2 0.00
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available