G23del (p.Gly23del) variant of SOX2 (Transcription factor SOX-2)

Name: SOX2 G23del (p.Gly23del) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-19
License: https://catvariant.com/terms-of-use

G23del (p.Gly23del) in SOX2 (Transcription factor SOX-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.

G23del (p.Gly23del) variant details

rs1560264163
gnomAD 3-181712417-GGGC-
Inframe Deletion
Variant Prioritization Score for Impact Estimate 0.76
CADD 20.80
Population evidence available
Structural context available
SOX2 High mobility group box domain domainome 1.0: score -0.99
Literature evidence available