Y88H (p.Tyr88His) variant of SOST (Sclerostin)
Y88H (p.Tyr88His) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
Y88H (p.Tyr88His) variant details
- p.Tyr88His
- gnomAD 17-43755722-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.35
- CADD 24.40
- PolyPhen-2 0.04
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available