Y88C (p.Tyr88Cys) variant of SOST (Sclerostin)
Y88C (p.Tyr88Cys) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
Y88C (p.Tyr88Cys) variant details
- p.Tyr88Cys
- gnomAD 17-43755721-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.58
- CADD 26.40
- PolyPhen-2 0.85
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available