Y78F (p.Tyr78Phe) variant of SOST (Sclerostin)
Y78F (p.Tyr78Phe) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
Y78F (p.Tyr78Phe) variant details
- p.Tyr78Phe
- gnomAD 17-43755751-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.265
- REVEL 0.14
- CADD 20.50
- PolyPhen-2 0.00
- SIFT 0.71
- Population evidence available
- Structural context available
- Literature evidence available