V75A (p.Val75Ala) variant of SOST (Sclerostin)
V75A (p.Val75Ala) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
V75A (p.Val75Ala) variant details
- p.Val75Ala
- gnomAD rs1405992033
- Missense
- Variant Prioritization Score for Impact Estimate 0.0881
- REVEL 0.10
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available