T86I (p.Thr86Ile) variant of SOST (Sclerostin)
T86I (p.Thr86Ile) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
T86I (p.Thr86Ile) variant details
- p.Thr86Ile
- gnomAD 17-43755727-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.791
- REVEL 0.85
- CADD 31.00
- PolyPhen-2 0.80
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available