T86A (p.Thr86Ala) variant of SOST (Sclerostin)
T86A (p.Thr86Ala) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
T86A (p.Thr86Ala) variant details
- p.Thr86Ala
- gnomAD 17-43755728-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.593
- REVEL 0.70
- CADD 24.40
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available