T16A (p.Thr16Ala) variant of SOST (Sclerostin)
T16A (p.Thr16Ala) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
T16A (p.Thr16Ala) variant details
- p.Thr16Ala
- gnomAD rs1439063195
- Missense
- Variant Prioritization Score for Impact Estimate 0.0951
- REVEL 0.11
- CADD 0.06
- PolyPhen-2 0.00
- SIFT 0.88
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available