S79R (p.Ser79Arg) variant of SOST (Sclerostin)
S79R (p.Ser79Arg) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
S79R (p.Ser79Arg) variant details
- p.Ser79Arg
- gnomAD 17-43755747-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.66
- CADD 27.60
- PolyPhen-2 0.99
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available