S76P (p.Ser76Pro) variant of SOST (Sclerostin)
S76P (p.Ser76Pro) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
S76P (p.Ser76Pro) variant details
- p.Ser76Pro
- gnomAD 17-43755758-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.512
- REVEL 0.49
- CADD 26.60
- PolyPhen-2 0.88
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available