S76F (p.Ser76Phe) variant of SOST (Sclerostin)
S76F (p.Ser76Phe) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
S76F (p.Ser76Phe) variant details
- p.Ser76Phe
- gnomAD 17-43755757-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.58
- REVEL 0.42
- CADD 28.00
- PolyPhen-2 0.90
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available