R87S (p.Arg87Ser) variant of SOST (Sclerostin)
R87S (p.Arg87Ser) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
R87S (p.Arg87Ser) variant details
- p.Arg87Ser
- gnomAD 17-43755725-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.661
- REVEL 0.61
- CADD 25.40
- PolyPhen-2 0.03
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available