R87L (p.Arg87Leu) variant of SOST (Sclerostin)
R87L (p.Arg87Leu) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
R87L (p.Arg87Leu) variant details
- p.Arg87Leu
- gnomAD 17-43755724-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.552
- REVEL 0.57
- CADD 24.60
- PolyPhen-2 0.25
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available