R87G (p.Arg87Gly) variant of SOST (Sclerostin)
R87G (p.Arg87Gly) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data, published literature, and structural context.
R87G (p.Arg87Gly) variant details
- p.Arg87Gly
- gnomAD 17-43755725-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.73
- REVEL 0.71
- CADD 26.20
- PolyPhen-2 0.34
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available