R81S (p.Arg81Ser) variant of SOST (Sclerostin)
R81S (p.Arg81Ser) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
R81S (p.Arg81Ser) variant details
- p.Arg81Ser
- gnomAD 17-43755743-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.692
- REVEL 0.70
- CADD 27.90
- PolyPhen-2 0.58
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available