R81R (p.Arg81Arg) variant of SOST (Sclerostin)
R81R (p.Arg81Arg) in SOST (Sclerostin) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
R81R (p.Arg81Arg) variant details
- p.Arg81Arg
- gnomAD 17-43755741-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.141
- CADD 8.47
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available