P93R (p.Pro93Arg) variant of SOST (Sclerostin)
P93R (p.Pro93Arg) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P93R (p.Pro93Arg) variant details
- p.Pro93Arg
- TOPMed rs1159168815
- gnomAD rs1159168815
- Missense
- Variant Prioritization Score for Impact Estimate 0.177
- REVEL 0.15
- CADD 12.80
- PolyPhen-2 0.01
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available