P93L (p.Pro93Leu) variant of SOST (Sclerostin)
P93L (p.Pro93Leu) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P93L (p.Pro93Leu) variant details
- p.Pro93Leu
- TOPMed rs1159168815
- gnomAD rs1159168815
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.17
- CADD 13.20
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available