P93A (p.Pro93Ala) variant of SOST (Sclerostin)
P93A (p.Pro93Ala) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
P93A (p.Pro93Ala) variant details
- p.Pro93Ala
- gnomAD 17-43755707-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.28
- MetaLR 0.27
- MetaSVM -0.90
- CADD 17.70
- PolyPhen-2 0.01
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available