N61D (p.Asn61Asp) variant of SOST (Sclerostin)
N61D (p.Asn61Asp) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
N61D (p.Asn61Asp) variant details
- p.Asn61Asp
- gnomAD rs1370224367
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.32
- CADD 23.80
- PolyPhen-2 0.13
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available