N52K (p.Asn52Lys) variant of SOST (Sclerostin)
N52K (p.Asn52Lys) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
N52K (p.Asn52Lys) variant details
- p.Asn52Lys
- TOPMed rs914981653
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.35
- CADD 22.60
- PolyPhen-2 0.08
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)
- Structural context available