N31S (p.Asn31Ser) variant of SOST (Sclerostin)
N31S (p.Asn31Ser) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
N31S (p.Asn31Ser) variant details
- p.Asn31Ser
- ExAC rs777424828
- gnomAD rs777424828
- Missense
- Variant Prioritization Score for Impact Estimate 0.683
- REVEL 0.71
- CADD 25.80
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available