L83M (p.Leu83Met) variant of SOST (Sclerostin)
L83M (p.Leu83Met) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
L83M (p.Leu83Met) variant details
- p.Leu83Met
- gnomAD 17-43755737-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.41
- CADD 23.10
- PolyPhen-2 0.39
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available