H84Q (p.His84Gln) variant of SOST (Sclerostin)
H84Q (p.His84Gln) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
H84Q (p.His84Gln) variant details
- p.His84Gln
- gnomAD 17-43755732-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.18
- CADD 22.90
- PolyPhen-2 0.05
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available