H68Q (p.His68Gln) variant of SOST (Sclerostin)
H68Q (p.His68Gln) in SOST (Sclerostin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
H68Q (p.His68Gln) variant details
- p.His68Gln
- ESP rs143755073
- ExAC rs143755073
- TOPMed rs143755073
- gnomAD rs143755073
- Missense
- Variant Prioritization Score for Impact Estimate 0.256
- REVEL 0.10
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 0.72
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.7e-05)
- Structural context available